Multi-Channel LNP Manufacturing Chip

Overview

Overview

Where screening chips stop, manufacturing chips start. A single chip carries 2–4 independent mixing channels running in parallel, taking LNP production from hundreds of millilitres up to hundreds of litres in one continuous run, with in-line dilution, in-line flow monitoring and in-line sampling built in.

Two usage models cover the full lifecycle — a single-use configuration for GMP closed-system production, and a reusable configuration for process development and pilot scale.

Configuration 1 — Single-Use (Disposable)

For GMP closed-system manufacturing: mRNA vaccine and gene therapy production runs where sterility and zero cross-contamination are non-negotiable.

Configuration 2 — Reusable

For R&D, iterative process development and pilot scale — anywhere formulations change faster than batches.

System specifications

Materials and specification notes

• System-level parameters above are taken from the manufacturer’s verified datasheet.
• Single-use chips are typically COC/COP; reusable chips are typically 316L stainless steel or glass/quartz. Exact material and grade are selected at order stage and confirmed with the factory at enquiry; batch-specific documentation ships with the COA.
• Some polymer chips tolerate simple cleaning and limited reuse — reuse policy follows the manufacturer’s instructions for the specific material and configuration ordered.
• Additional quality-system documentation is available on request during supplier qualification.

Choosing a configuration

Use single-use when: GMP production, sterile filling, regulated batches, fast changeover between products. Use reusable when: process R&D, pilot campaigns, frequent formulation changes, long-running optimisation programmes.

Both configurations share the channel count options and all system specifications above; enquiry with your target batch size and we will recommend a channel / configuration combination.