Lung-Targeted RNA Transfection Kit (Ready-to-Use LNP)
Ready-to-use lung-targeted LNP kit — one mixing step, no microfluidics, no incubation, ethanol-free. Up to 94% lung accumulation after IV administration in animals. siRNA, gRNA, mRNA and circRNA compatible.
Catalog no. TD-LUNG-03 / 05 / 10 · Ships with certificate of analysis
For Research Use OnlyOverview
Overview
A ready-to-use kit for lung-targeted RNA delivery that needs no specialised equipment. RNA and reagent are combined in a single tube; ten gentle pipettings or 2–3 seconds of vortexing self-assemble the mixture into LNPs, ready for intravenous administration in animals — with the majority of the dose accumulating in the lung.
The kit contains transfection reagent, buffers and a firefly luciferase mRNA positive control. No microfluidic instrument, no incubation step, no ethanol — in vivo performance comparable to microfluidic-prepared LNPs, without the equipment investment.
Kit sizes and contents
| Size | Part number |
|---|---|
| 0.3 mL | TD-LUNG-03 |
| 0.5 mL | TD-LUNG-05 |
| 1.0 mL | TD-LUNG-10 |
Specifications
| Lung targeting | up to 94% accumulation in lung, markedly reduced non-specific transfection in other organs |
|---|---|
| Encapsulation efficiency | up to 80% (trace samples) |
| In vivo performance | comparable to microfluidic-prepared LNPs |
| RNA types | siRNA, gRNA, mRNA, circRNA |
| Administration | intravenous injection (animal studies) |
| Reference dose (mouse) | 0.5–2.0 mg/kg; reagent : RNA = 1 : 1 |
| Ethanol | ethanol-free formulation |
| Sterilisation | 0.2 μm filtered |
| Lipids | biodegradable, biocompatible proprietary formulation |
| Intended use | For Research Use Only |
Shipping and storage
| Shipping | ambient (≤25 °C) |
|---|---|
| Reagent and buffers | 2–8 °C refrigerated — do not freeze |
| Fluc mRNA positive control | −20 °C on arrival (lyophilised powder; brief spin before opening) |
| Prepared RNA–LNP complex | use within 2 h at room temperature — do not freeze |
Key features
- Ready-to-use, one step — single mixing step, no equipment, no incubation: 10 pipettings or 2–3 s vortex
- Highly lung-selective — up to 94% accumulation in lung, with significantly reduced transfection in liver, spleen and other non-target organs
- Ethanol-free, biodegradable — biocompatible lipids, 0.2 μm filtered, low toxicity
- Broad RNA compatibility — siRNA, mRNA, gRNA and circRNA
- Microfluidic-grade performance — matches instrument-prepared LNPs in vivo without any equipment
Applications
Pulmonary fibrosis, asthma and respiratory disease research; lung gene editing and airway nucleic acid drug screening; in vivo lung-targeted delivery of mRNA / siRNA in animal models.
Notes
- For Research Use Only. This kit is not a drug and not a medical device; it is supplied exclusively for research applications.
- Certification documents are available on request and verifiable by certificate number.
- FOB pricing, MOQ and lead time are quoted at enquiry.
| Product | Lung-Targeted RNA Transfection Kit (Ready-to-Use LNP) |
|---|---|
| Catalog no. | TD-LUNG-03 / 05 / 10 |
| Category | Targeted Delivery |
| Documentation | Certificate of analysis provided with every lot |
| Intended use | For Research Use Only (RUO). Not for diagnostic or therapeutic use. |
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